rabies antibody levels in pregnant women and their newborns after rabies post-exposure prophylaxis
نویسندگان
چکیده
background: rabies is a fatal infectious disease and rabies post-exposure prophylaxis is the method of choice for prevention of human rabies. case series: we report rabies antibody levels in cord blood and also in serum of pregnant women who were bitten by suspected animals to rabies and were immunized by purified vero cell rabies vaccine (pvrv) and human rabies immunoglobulin (hrig) serum. during the years of 2007-2010, six pregnant women by the age range of 22-35 years were admitted in treatment and prevention of rabies center in pasture institute of iran, in tehran. among them two cases were at first trimester, one at second trimester and three at third trimester of conception. the interval between biting with delivery was 5-265 days (mean 121 days). conclusion: results of immunoglobulin illustrate that levels of rabies antibody in maternal sera with the fetus are not equal and uniform but it is proved that baby will find efficient immunity as well with minimum protective level of 0.5 iu/ml in all cases except a newborn whom had been born just 5 days after the mother’s immunization and in a shorter time than the appropriate immunization of the mother who had received her second vaccination courses.
منابع مشابه
Rabies antibody levels in pregnant women and their newborns after rabies post-exposure prophylaxis
BACKGROUND Rabies is a fatal infectious disease and rabies post-exposure prophylaxis is the method of choice for prevention of human rabies. CASE SERIES We report rabies antibody levels in cord blood and also in serum of pregnant women who were bitten by suspected animals to rabies and were immunized by purified Vero cell rabies vaccine (PVRV) and Human Rabies immunoglobulin (HRIG) serum. Dur...
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introduction rabies is a fatal disease and has a threatening risk for the public health. immunosuppression is related to a wide variety of diseases. it is recommended that immunosuppressed patients receive the full post-exposure vaccination, concerning that the immune response may be inadequate. the aim of this study is to determine the level of rabies neutralizing antibody in immunosuppressed ...
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1. Popescu GA, Fuerea R, Benea E. Meningitis due to an unusual human pathogen: Streptococcus equi subspecies equi. South Med J. 2006;99:190–1. 2. Korman TM, Boers A, Gooding TM, Curtis N, Visvanathan K. Fatal case of toxic shock-like syndrome due to group C Streptococcus associated with superantigen exotoxin. J Clin Microbiol. 2004;42:2866–9. 3. Fernandez E, Blume V, Garrido P, Collins MD, Mate...
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BACKGROUND Thousands of human deaths from rabies occur annually despite the availability of effective vaccines following exposure, and for disease control in the animal reservoir. Our aim was to assess risk factors associated with exposure and to determine why human deaths from endemic canine rabies still occur. METHODS AND FINDINGS Contact tracing was used to gather data on rabies exposures,...
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عنوان ژورنال:
international journal of reproductive biomedicineجلد ۱۰، شماره ۲، صفحات ۱۶۱-۰
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